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Insulin Resistance

July 14th, 2015 | by Great Britain Association
Insulin Resistance
Insulin resistance

Insulin resistance occurs when insulin levels are sufficiently high over a prolonged period of time causing the body’s own sensitivity to the hormone to be reduced.

Once the body starts to get resistant to insulin, it can be a difficult process to reverse because the knock on effect of insulin resistance.

Higher circulating levels of insulin in the blood stream and weight gain help to further advance insulin resistance.

What is insulin resistance?

Insulin resistance is closely linked with inflammation, which is the body’s attempt to heal itself.

It is thought that in prediabetes and type 2 diabetes the body’s immune system releases a chemical called cytokines which is thought to interrupt with the action of insulin.

Therefore, lower insulin sensitivity and increasing insulin resistance.

Type 2 diabetes that is brought on by obesity is a result of chronic inflammation.

Symptoms of insulin resistance

One of the earliest and most noticeable symptoms of insulin resistance is weight gain, particularly around the middle.

Further symptoms include:

  • Lethargy
  • Hunger
  • Difficulty concentrating (brain fog)
  • High blood pressure is another common symptom which is caused by high circulating levels of insulin in the blood

If insulin resistance develops into prediabetes or type 2 diabetes, the symptoms will include include increased blood glucose levels and more of the classic symptoms of type 2 diabetes.

Causes of insulin resistance

Research is continuing to look more closely into how insulin resistance develops.

It is thought that the principle cause of insulin resistance is obesity. One theory suggests that central obesity (too much fat around the belly) causes the fat cells to become starved of oxygen and die.

It is thought that the body reacts with an inflammatory response which then sets off the start of insulin resistance.

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